To answer the question in the title, I created a new cell style. The new cell style was similar to Text, in that text could be edited within the new cell. However, the new style specified a CellEvaluationFunction for the cell. Let's call it f. This means that when the cell is evaluated, it returns the value f[_str_], where _str_ is the string contents of the cell.

I knew then that the definitive answer to my question is YES! My reasoning was as follows:  If f[_str_] returns Null then the new cell will not only look like a Text cell, it will also print no Output cell in the notebook (also like a Text cell). Instead of printing output, f[_str_] could write _str_ to a file, have it processed by pdflatex, and then the resulting PDF file could be displayed by an auto-reloading PDF viewer. 

A notebook that contained _just one such cell_ would be equivalent to something like [TeXworks](http://www.tug.org/texworks/), and would already have built-in spell-check, find-and-replace, and a host of keyboard shortcuts. All this from just a single cell style definition and one 3 line function,
```
   f[str_] := (WriteString["demo.tex", str];  
               Close["demo.tex"];  
               RunProcess[{"pdflatex", "demo.tex"}];)  
```
Of course, Mathematica allows for a few improvements to the one-cell-editor idea: A multi-cell version of the editor can offer built-in notebook features  such as notebook headings and collapsible sections that surpass those of many LaTeX editors. If one also factors in the potential for interleaved Mathematica calculations, and the possibility of having selected results automatically translated to LaTeX and written to file, then the possibilities become quite awesome... 

...now, several years later, I'm happy to announce that
[EnableTeX](https://ahnorton.com/enabletex/) has been released :)

A user guide for EnableTeX is available from the home page:
[https://ahnorton.com/enabletex/](https://ahnorton.com/enabletex/)

Licenses for EnableTeX are not free and the code may not be distributed. Nevertheless, licensees have access to the source code, and are allowed to modify their copies of the code if they want to.