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Solving a system of ODEs (Schroedinger equation for a two-level system)

I want to solve the time-dependent Schroedinger equation:

$$ i\partial_t \psi(t) = H(t)\psi(t) $$

for matrix, time-dependent $H(t)$ and vector $\psi$.

What is an efficient way of doing this so that it efficiently scales to high-dimensional spaces?