I have got error with large-scale Problems that needs a solution by LinearProgramming, I am working on TSP Problem and I write the Linear Formulation for this Problem (Note: I know that there is a function in Mathematica "FindShortestTour" can give me the solution of this problem, but I need to solve the linear formula by myself), I write a code that can generate automatically the formula and give it to Function like NMinimize, I have no problem when the number of variables and constraints are small, it works very nice and there are no errors, The error appears when the size of problem is large so it gives me this error
"kernel is not responding to a dynamic evaluation"
for example when the number of cities in TSP is 50 we have 2500+50 variables and nearly 2500 constraint, I try to use NMinimize but it gives the error above then I try to use LinearProgramming Function and it also gives the same error I read in documentation that method simplex is not useful for large-scale problem and we must use InteriorPoint, I try to use it, but Mathematica gives error that it is unuseful when we have constraint that variable must have integer value (that is my case ), I try to use FindMinimum (although it gives local optimum not global which I want) and it also gives the same error, why this appears, I deal with these functions in other problems and sometimes it takes too long time (like 10 hours or days) to give solution but it last gives result and this is nice why here it stops and cannot give any solution what is the method to solve Linear large-scale problems in Mathematica please help me