What you are seeing are the kind of problems that you run into if you attempt to set both ImageSize
and AspectRatio
.
Graphics[
Line[{{0, 0}, {0, 1}}],
ImageSize -> {50, 150},
AspectRatio -> 1,
Frame -> True
]

ImageSize
is the full size of the graphics, e.g. the orange box in the image here above. AspectRatio
is the ratio of the box that frames the graphics. You're specifying that the box should have the aspect ratio 1, i.e. be a square, but the image should have the aspect ratio 150/50=3. Clearly, there's going to be a lot of white space on the top and bottom of the graphics to make that happen.
We can make the figure fill the image by making the aspect ratio of the figure match the aspect ratio of the image:
Graphics[
Line[{{0, 0}, {0, 1}}],
ImageSize -> {50, 150},
AspectRatio -> 150/50,
ImagePadding -> 0,
Frame -> True
]

Now the framed box takes up the entire area of the image. Unfortunately, it leaves the axis tick labels outside the plot. To fix this, ImagePadding
is used:
Graphics[
Line[{{0, 0}, {0, 1}}],
ImageSize -> {50, 150},
AspectRatio -> 150/50,
ImagePadding -> {{20, 5}, {20, 5}},
Frame -> True
]

This fixed the labels, but now we see that we have white space around the image again. This is because when we add padding, we decrease the size of the figure by the same amount. This is as opposed to adding margin, which keeps the size of the figure the same but increases the image size. I've made a tool to explore these effects, available here.
We need to adapt the aspect ratio according to our plot padding:
Graphics[
Line[{{0, 0}, {0, 1}}],
ImageSize -> {50, 150},
AspectRatio -> (150 - 25)/(50 - 25),
ImagePadding -> {{20, 5}, {20, 5}},
Frame -> True
]

Now the figure fills up the entire image again. I hope this gives you an understanding of the issues that you are facing.
As for the size of the points in your images, you should note that the sizes of graphics primitives are given in the coordinate system of the figure. If you look at the axes of the frame, you will see that in this coordinate system the two points are the same size. One appears larger than the other because of how the coordinate system has been stretched in one of the images compared to the other.