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I am pretty dumbfolded on this one and there seem to be virtually no clues around the net. The only thing vaguely related is a fairly similar (unsuccessful) question on reddit:

https://m.reddit.com/r/Mathematica/comments/1dpcev/help_me_mathematica_wont_start_anymore_and_i_need/

I am running Mathematica 8 using a school licence server - it crashed the other day because my VPN session ran out. After that I have no longer been able to launch successfully.

Multiple uninstall / registry clean attempts have remained unsuccessful - any ideas / suggestions?

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  • $\begingroup$ Have you contacted Wolfram Support? This seems like a question that they would be better equipped to answer. $\endgroup$ – MarcoB Nov 30 '15 at 19:12
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OK - I was successful on my own. Since the Wolfram Support does not mention Error 499 I will put the answer link here.

http://support.wolfram.com/kb/12464

Deleting C:\Users\USERNAME\AppData\Roaming\Mathematica did the trick for me.

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    $\begingroup$ Errors of this kind during startup are usually due to the corruption of one of the files in $UserBaseDirectory. Deleting that directory (except, perhaps, the Licensing subfolder) usually does the trick. $\endgroup$ – Stefan R Nov 30 '15 at 23:06
  • $\begingroup$ Yes that did the trick - I was mostly surprised not to find any mention of the prominently reported error code anywhere. $\endgroup$ – CMichael Nov 30 '15 at 23:32

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