You can use the definition of Laplace. Assuming zero initial conditions, replace $s$ with $\frac{dy}{dt}$ and $s^2$ with $\frac{d^2y}{dt^2}$ and so on.
tfToDiff[tf_, s_, t_, y_, u_] := Module[{rhs, lhs, n, m},
rhs = Numerator[tf];
lhs = Denominator[tf];
rhs = rhs /. m_. s^n_. -> m D[u[t], {t, n}];
lhs = lhs /. m_. s^n_. -> m D[y[t], {t, n}];
lhs == rhs
]
Now call it
tf = C0 s/(R0 C0 s + 1);
eq=tfToDiff[tf, s, t, y, u]

$y(t)$ is your output, and $u(t)$ is the input. (these are what go in the transfer function when you write $\frac{Y(s)}{U(s)}=\dots$. You'd have to replace this when the actual $u(t)$ to solve the differential equation. For step input, (i.e. $u(t)=\text{unit step}$)
eq = eq /. u'[t] -> UnitStep'[t];
DSolve[{eq, y[0] == 0}, y[t], t]

Another Example
tf = (5 s)/(s^2 + 4 s + 25);
tfToDiff[tf, s, t, y, u]
