Mathematica 12.1 and 12.2 were benchmarked, the winner is random but two tests stand out as having a distinct trend, test-1 and test-11.

HP ENVY Phoenix 850se Win 10 Desktop PC
Product number: M0K57AV#ABA
4th Generation Intel(R) Core(TM) i7-5820K processor hexa-core [3.3GHz, 15MB Shared Cache]
32GB DDR4-2133 DIMM (4x8GB) RAM
NVIDIA GTX 745 4GB DDR3 FH GFX
Operating System:   Windows 10 Home, 64-bit
DirectX version:    12.0 
GPU processor:      GeForce GTX 745
Driver version:     456.71
Driver Type:        DCH
Direct3D API version:   12
Direct3D feature level: 11_0
CUDA Cores:     384 
Core clock:     1032 MHz 
Memory data rate:   1.80 Gbps
Memory interface:   128-bit 
Memory bandwidth:   28.80 GB/s
Total available graphics memory:    20428 MB
Dedicated video memory: 4096 MB DDR3

12.2 vs 12.1 (12.2 wins this round)

Mathematica 12.1

{"MachineName" -> "desktop-n3opac6", 
 "System" -> "Microsoft Windows (64-bit)", 
 "BenchmarkName" -> "WolframMark", "FullVersionNumber" -> "12.1.0", 
 "Date" -> "December 23, 2020", "BenchmarkResult" -> 2.337, 
 "TotalTime" -> 5.924, "Results" -> {{"Data Fitting", 0.409}, 
   {"Digits of Pi", 0.308}, {"Discrete Fourier Transform", 0.578}, 
   {"Eigenvalues of a Matrix", 0.487}, {"Elementary Functions", 0.555}, 
   {"Gamma Function", 0.442}, {"Large Integer Multiplication", 0.527}, 
   {"Matrix Arithmetic", 0.352}, {"Matrix Multiplication", 0.253}, 
   {"Matrix Transpose", 0.429}, {"Numerical Integration", 0.677}, 
   {"Polynomial Expansion", 0.062}, {"Random Number Sort", 0.159}, 
   {"Singular Value Decomposition", 0.39}, {"Solving a Linear System", 
    0.296}}}

Mathematica 12.2

{"MachineName" -> "desktop-n3opac6", 
 "System" -> "Microsoft Windows (64-bit)", 
 "BenchmarkName" -> "WolframMark", "FullVersionNumber" -> "12.2.0", 
 "Date" -> "December 23, 2020", "BenchmarkResult" -> 2.358, 
 "TotalTime" -> 5.87, "Results" -> {{"Data Fitting", 0.446}, 
   {"Digits of Pi", 0.312}, {"Discrete Fourier Transform", 0.566}, 
   {"Eigenvalues of a Matrix", 0.479}, {"Elementary Functions", 0.548}, 
   {"Gamma Function", 0.43}, {"Large Integer Multiplication", 0.438}, 
   {"Matrix Arithmetic", 0.343}, {"Matrix Multiplication", 0.241}, 
   {"Matrix Transpose", 0.423}, {"Numerical Integration", 0.723}, 
   {"Polynomial Expansion", 0.063}, {"Random Number Sort", 0.17}, 
   {"Singular Value Decomposition", 0.399}, {"Solving a Linear System", 
    0.289}}}