Don't worry about whether these are trivial questions: they are good opportunities to explain a little more about Mathematica's syntax.
The first point is that what you already had works fine. You can confirm this using FullForm.
If[cond1 && cond2 && cond3, a, b] // FullForm
(*If[And[cond1,cond2,cond3],a,b]*)
If you preferred, you could type out the And construction explicitly.
J.M.'s comment invokes the Apply function to change the Head of a List of things, in this case the conditions, to And.
And @@ {cond1, cond2, cond3} // FullForm
(* And[cond1,cond2,cond3] *)
Or equivalently
FullForm[Apply[And, {cond1, cond2, cond3}]]
(* And[cond1,cond2,cond3] *)
The FullForm is just for explication; you wouldn't use it in normal operations. So the short syntax for the above is:
And @@ {cond1, cond2, cond3}
(* cond1&&cond2&&cond3 *)
The usefulness of storing your list of conditions as a list is that it is then easier to use various other list-manipulation techniques to get those subsets of conditions mentioned in your question.
And @@ (Most@{cond1, cond2, cond3})
(* cond1&&cond2 *)
conds = {cond1, cond2, cond3}; If[And @@ conds, a, b]? – J. M.♦ Oct 6 '12 at 13:23